Do acid reflux medications cause dementia?

Do acid reflux medications cause dementia?

Do acid reflux medications cause dementia?

Millions of people around the world use acid suppressants called proton pump inhibitors for conditions like heartburn, gastritis and stomach ulcers. Researchers at Karolinska Institutet in Sweden now report that how the long-term use of these drugs could increase the risk of developing dementia.

What medications can contribute to dementia?

The researchers found that anticholinergic drugs in general were associated with a higher risk of dementia. More specifically, however, anticholinergic antidepressants, antipsychotic drugs, anti-Parkinson's drugs, bladder drugs, and epilepsy drugs were associated with the highest increase in risk.

What are the long term effects of taking omeprazole?

Despite their ease of availability and common use, PPIs can have severe side effects. The long-term consequences of chronic PPI use include the potential increased risk of hypocalcemia, hypomagnesemia, Clostridium difficile infections, and pneumonia.

Are there any acid reducers that cause dementia?

  • Prilosec and Prevacid probably aren't causing mental decline, as once suspected. What Is Dementia? If you've been taking an acid-reducer and showing some signs of mental decline, you’re hardly alone.

Are there any heartburn medications that cause dementia?

  • Research finds association among users over age 75, but can't prove the medications cause memory problems MONDAY, Feb. 15, 2016 (HealthDay News) -- A popular class of heartburn medications might raise a senior's risk of dementia, a new study suggests. Called proton pump inhibitors (PPIs), this group of drugs includes Prilosec, Nexium and Prevacid.

How are medications related to the risk of dementia?

  • Those who had taken any medication with anticholinergic activity were 11% more likely to be eventually diagnosed with dementia; for those drugs with the most anticholinergic effects, the risk of dementia was 30% greater.

Is there a link between anticholinergic drugs and dementia?

  • Still, there is reason to be concerned about the possibility that anticholinergic drugs contribute to the risk of dementia. Acetylcholine is involved in memory and learning, and past research has demonstrated lower levels of acetylcholine in the brains of people with Alzheimer’s disease (the most common cause of dementia in the elderly).

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