Does omeprazole lead to dementia?

Does omeprazole lead to dementia?

Does omeprazole lead to dementia?

The patients who had been regularly taking a PPI, such as omeprazole (Prilosec), pantoprazole (Protonix), lansoprazole (Prevacid), esomeprazole (Nexium) and rabeprazole (AcipHex), had a significantly increased risk of incident dementia compared with patients who did not take the medication.

Do PPI drugs cause dementia?

Recent clinical studies have shown that proton pump inhibitors (PPIs) are associated with risk of dementia, including AD. However, a recent case-control study reported decreased risk of dementia.

Do antacids cause Alzheimer's?

A very large meta-analysis of 9 observational studies including more than 6,000 people reported that regular antacid use was not associated with Alzheimer's disease [18]. Even when the analysis was confined to people who used antacids regularly for over 6 months, there was no association with Alzheimer's.

Do proton pump inhibitors increase the risk of dementia?

Some experimental18 and clinical19 studies in recent years have found that proton pump inhibitors (PPIs) are associated with an increased risk of dementia and AD. PPIs block the H+ and K+-ATPase and, as a result, suppress the secretion of gastric acid.

Are there any acid blockers that cause mental decline?

  • From the WebMD Archives. Aug. 3, 2007 - Long-term use of H2 blockers, including Axid, Pepcid, Tagamet, and Zantac, may increase the risk of mental decline in later life.

Are there any acid reducers that cause dementia?

  • Prilosec and Prevacid probably aren't causing mental decline, as once suspected. What Is Dementia? If you've been taking an acid-reducer and showing some signs of mental decline, you’re hardly alone.

Is there a link between H2 blockers and dementia?

  • The results are surprising enough that at least one leading expert on aging, Dr. Malaz Boustani, plans to share the findings with older patients who are using PPIs. Boustani said earlier studies have linked another type of antacid, H2 blockers, with an increased risk of dementia.

How are proton pump inhibitors linked to dementia?

  • Called proton pump inhibitors (PPIs), this group of drugs includes Prilosec, Nexium and Prevacid. They work by lowering the amount of acid produced by the stomach. But German researchers found that people 75 or older who regularly take the medications had a 44 percent increased risk of dementia, compared with seniors not using the drugs.

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